CVS closing 270 stores in 2025: full list of locations affected by retail realignment

CVS store closures part of long-term restructuring strategy

CVS has confirmed that it will close 271 stores in 2025 as part of its ongoing national retail restructuring effort. This move follows the closure of approximately 900 locations between 2022 and 2024. In its February annual report, the company detailed an “enterprise-wide restructuring plan” aimed at streamlining operations and adapting to evolving consumer needs.

A spokesperson for CVS told Newsweek that the closures are based on a range of criteria, including local population shifts, consumer buying behavior, pharmacy and store density, pharmacy access, and community health data. According to the company, these changes are not a response to industry pressures but rather a planned strategy announced in 2021.

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CVS says the closures will allow for optimization of its existing store footprint and improve customer service delivery. The company emphasized that 85 per cent of Americans will continue to live within 10 miles of a CVS Pharmacy even after the closures.

Full list of CVS closures confirmed for 2025

CVS has not released a complete nationwide list of all store closures for 2025. However, data compiled from The Krazy Coupon Lady and local news sources has identified 34 locations that have either closed or announced scheduled closures. Additional closures were reported by Newsweek from state and local media. The impacted states and addresses include:

Alabama

• 2901 Morgan Rd., Bessemer
  
  
  
• 3303 Clairmont Ave., Birmingham
  
  
  

California

• 499 Haight St., San Francisco
  
  
  
• 1701 K St., Sacramento
  
  
  

Florida

• 3090 S. Monroe St., Tallahassee
  
  
  
• 13300 E. Colonial Dr., Orlando
  
  
  
• 2201 Edgewater Dr., Orlando
  
  
  

Georgia

• 439 Highland Blvd., Atlanta
  
  
  

Illinois

• 8639 S. Cicero Ave., Chicago
  
  
  
• 401 W. Armitage Ave., Chicago
  
  
  
• 2000 Skokie Valley Rd., Highland Park
  
  
  

Iowa

• 2420 Lincoln Way, Ames
  
  
  
• 215 Euclid Ave., Des Moines
  
  
  

Massachusetts

• 55 Summer St., Boston
  
  
  

Michigan

• 28774 Gratiot Ave., Roseville
  
  
  
• 27700 Harper Ave., St. Clair Shores
  
  
  

Missouri

• 2435 Independence Ave., Kansas City
  
  
  
• 9433 Manchester Rd., Saint Louis
  
  
  
• 4531 Troost Ave., Kansas City
  
  
  

New York

• 955 Payne Ave., North Tonawanda
  
  
  
• 153 Central Ave., Albany
  
  
  
• 1026 Madison Ave., Albany
  
  
  
• 1241 Lexington Ave., New York
  
  
  
• 1654 Richmond Ave., Staten Island
  
  
  

North Carolina

• 201 W. 4th St., Winston-Salem
  
  
  

Ohio

• 10825 Kinsman Rd., Cleveland
  
  
  

Pennsylvania

• 125 E. Main St., Plymouth
  
  
  

Virginia

• 10390 Willard Way, Fairfax
  
  
  

Washington, D.C.

• 1117 10th St. NW
  
  
  
• 1100 4th St. SW
  
  
  
• 400 Massachusetts Ave. NW
  
  
  
• 1515 New York Ave. NE
  
  
  
• 4500 Wisconsin Ave. NW
  
  
  
• 7828 Georgia Ave. NW
  
  
  

Additional locations reported by Newsweek include:

Indiana – 9550 Allisonville Rd., Indianapolis
Maryland – 1000 S. Charles St., Baltimore; 7235 Wisconsin Ave., Bethesda; 34 N. Cannon Ave., Hagerstown (closing June 26)
Texas – 3890 Phelan Blvd., Beaumont

Also read: JCPenney closes seven stores nationwide amid ongoing retail challenges, check if you are affected

New CVS openings planned despite ongoing closures

Despite the ongoing retail consolidation, CVS stated it plans to open 30 new pharmacy locations in 2025. These include pharmacy counters within select Target stores, maintaining a widespread presence in both urban and suburban markets.

Separately, CVS has raised concerns about new pharmacy legislation in Arkansas, where Governor Sarah Huckabee Sanders recently signed a bill limiting ownership of pharmacies by Pharmacy Benefit Managers. CVS has warned the law could impact its 23 locations in the state.

CVS maintains that store closures are part of a strategic national realignment intended to improve service quality and retail efficiency.